Moxifloxacin versus Ampicillin / Sulbactam in the treatment of aspiration pneumonia and primary lung abscess

Objective: Aspiration pneumonia (AP) and primary lung abscess (PLA) are rare diseases, which can be associated with life-threatening complications. The main cause of these diseases is an aspiration of infectious material from the oral cavaty or stomach. There is limited information on optimal antibacterial therapeutic regimens, which schould include anaerobic bacteria. We compared clinical and bacteriologic efficacy and safety of moxifloxacin (MOX) with that of ampicillin/sulbactam (AMP/SBT) in the treatment of AP and PLA. Methods: Prospective open-label randomized multicenter trial including patients with pulmo…