Right Temporal Cerebral Dysfunction Heralds Symptoms of Acute Mountain Sickness

Background: We prospectively investigated the effects of high altitude mountain trekking on brain function measured by electroencephalography (EEG) and transcranial doppler sonography (TCD) in relation to endexpiratory CO2 (EtCO2) peripheral O2 saturation (SaO2) and symptoms of acute mountain sickness (AMS). Methods: The studiy was performed during a common trekking route at the Khumbu Himal, Nepal, from Lukla (2865m) to the Silver Pyramid (5050m) near the Everest Base Camp. EEG and TCD were performed at baseline (100m), and at altitudes of 3440m and 5050m. SaO2, EtO2 and Lake-Louise-AMS Score was evaluated dail…