Relationships between autonomic function and 24-hour blood pressure profile in patients with primary biliary cirrhosis

Introduction: In order to further clarify the supposed connection between the systemic hypotension – characterizing hyperdynamic circulation – and the autonomic function, we aimed to evaluate the relationship between autonomic function and 24-hour blood pressure profile in patients with primary biliary cirrhosis. Patients and methods: Twenty-four AMA M2 positive female patients with PBC and twenty age-matched healthy female subjects were studied. Five standard cardiovascular reflex-tests and 24-hour heart rate variability (HRV) analysis were performed to define autonomic function. Results: Using standard cardiov…