Probabilistic tractography of cortical connectivity of the human hippocampus and the anatomy of hippocampal-thalamic connections

Introduction: The widespread cortical connections of hippocampal pathways involved in learning, memory and emotion, and the anatomical connections between thalamic nuclei and the hippocampus are mainly known from tracing studies in animals. Recent diffusion tensor imaging (DTI) techniques are promising tools for tracing fiber tracts in the human brain in vivo and have been demonstrated to correspond well with neuroanatomical knowledge. Methods: High angular resolution DTI was acquired on a 3T scanner in 11 healthy subjects by using echo planar imaging (isotropic distribution along 60 directions, b value 1,000s·m…