Imaging human supraspinal locomotor control by positron emission tomography
A Zwergal, C La Fougere, T Brandt, M Strupp, K Jahn · Aktuelle Neurologie · 2008 · Heft 09
Bibliografische Angaben
Zusammenfassung
Objectives: Characterisation of the supraspinal network of locomotor centers in humans during real locomotion. Methods: Healthy subjects (n=20) had to walk with a medium velocity (of about 1m/s) in a basement floor providing uniform visual environment for 10 minutes. Then [18F]-Fluoro-desoxyglucose ([18F]-FDG, max. 200MBq) was injected intravenously while the subject continued walking for further 10 minutes. Imaging started 30 minutes after tracer injection. An automated analysis of the [18F]-FDG-PET images generated standardized three-dimensional stereotactic surface projections of the individual dataset follow…