Treatment of spasticity of different origins with botulinum toxin A: long-term results

Introduction: Spasticity can cause significant disability in affected patients. We present a retrospective analysis of 137 patients with spasticity of different pathogenesis who have been treated with botulinum toxin type A (BTX, Botox® or Dysport®) in our movement disorder clinic between 1993 and 2007. Methods: BTX dose per treatment and per treated muscle, global clinical improvement (GCI; 0 to 3; 0=no effect, 3=marked improvement), side effects, latency of response and duration of response were recalled from our database. Statistical analysis was carried out using SPSS v 14.0 (SPSS, Chicago, IL). Results: The…