Postural deficits in Huntington's disease are partly different from those in Parkinson's disease

Huntington's disease (HD) is characterized clinically by abnormal, involuntary movements (chorea) associated with psychiatric signs and progressive dementia. Motor disturbances involve both hyperkinetic motor signs (chorea) and a progressive, akinetic-rigid syndrome at more advanced stages. Clinical features of the disturbed stance and gait in HD were reported to resemble (see e.g. Delval A. et al., J Neurol 2006; 253: 73–80) those in Parkinson's disease (PD). Therefore, we studied postural control in subjects with manifest HD using a model based approach and compared the results to those of patients with PD. Me…