The role of surgical outcome as prognostic factor in advanced epithelial ovarian cancer. A project of the AGO-OVAR and GINECO – Prognostic factor surgical outcome in advanced ovar…
P Harter, A Reuss, J Pfisterer, E Pujade-Lauraine, I Ray, A du Bois · Geburtshilfe und Frauenheilkunde · 2008 · Heft 09
Bibliografische Angaben
Zusammenfassung
Purpose: Primary surgery followed by platinum-taxane based chemotherapy is the standard therapy in advanced ovarian cancer. However, the prognostic role of complete and so-called optimal and suboptimal debulking and its interaction with biological factors is still not fully defined. Patients and methods: Exploratory analysis of three prospective randomized trials (AGO-OVAR 3, 5 & 7) investigating platinum-taxane based chemotherapy regimens in advanced ovarian cancer and conducted between 1995 and 2002. Results: 3,126 pts were analysed. Approximately one third each fulfilled criteria for complete resection (group…