Maspin–A new prognostic marker for ovarian cancer?

Objective: Maspin, a serin protease inhibitor is differentially expressed among different types of cancer. Only few data concerning the expression of maspin in ovarian cancer (OC) do exist. To find out if maspin could serve as an prognostic marker in OC patients; this study evaluates the maspin expression (ME) and its correlation to tumor clinical-pathological factors and survival. Material and Methods: Paraffin embedded tissues of 87 patients diagnosed with OC were arranged in a tissue micro array. Purified mouse anti-human maspin monoclonal antibody directed against nuclear and cytoplasmic located maspin was a…