Insulin growth factor 1 in normal and growth – retarded fetuses

Objective: To establish a reference range of insulin growth factor1 (IGF-I) levels in normal fetuses and to assess whether intrauterine growth retardation is associated with increased or decreased IGF- I levels Method: Retrospective analysis of blood samples collected from n=45 fetuses who underwent blood sampling at 18–38 weeks gestation was performed: 25 fetuses, who were considered controls, were appropriately grown for gestational age and were found unaffected by the condition for which they were tested, the remainder (n=20) underwent fetal blood sampling to assess fetal genotypic following ultrasonic diagno…