The resting brain in blind subjects – an fMRI study with eyes open and closed in darkness
K Hüfner, T Stephan, V Flanagin, R Kalla, A Deutschländer, S Glasauer, G Fesl, M Strupp, T Brandt · Klinische Neurophysiologie · 2009 · Heft 03
Bibliografische Angaben
Zusammenfassung
Objective: It has been shown in normal subjects that opening the eyes in darkness without external visual stimulation increases activity in the ocular motor and attentional systems. By contrast, closing the eyes causes a relative signal increase in multiple sensory areas such as the visual, somatosensory, vestibular, auditory, and gustatory cortical areas. These two states of „resting“ activity of the human brain in complete darkness, which can be imaged using fMRI, were termed the „exteroceptive“ state (contrast OPEN>CLOSED) and the „interoceptive“ state (contrast CLOSED>OPEN). In the present study we investiga…