Febrile infection responsive epileptic syndrome (FIRES): A novel non-encephalitic encephalopathy in children admitted to ICU?
A van Baalen, R Boor, U Stephani, U Stephani, M Häusler, G Kluger · Zeitschrift für Geburtshilfe und Neonatologie · 2009 · Heft 04
Bibliografische Angaben
Zusammenfassung
Introduction: Even though status epilepticus requiring intensive care occurs after simple febrile infection and detection of pathogens in CSF fails, an encephalitis is generally the presumed cause. Methods: Multicenter case series. Results: From 1997 to 2008, 16 previously healthy children aged 3–15 (median 6) years presented with status epilepticus or repetitive seizures 2–14 (median 5) days after fever onset (10 children with airway infections). Pathogens were detected in serum or nasopharyngeal aspirate of 5 children (RSV, parvovirus B19, rhinovirus, echovirus, Epstein-Barr virus). CSF studies revealed 0–42 (…