CareLit Fachartikel

Treatment of a Newborn with Urea-Cycle-Disorder and Cerebral Edema with Venovenous Hemodiafiltration and Therapeutic Hypothermia

R Vargha, G Mostafa, M Hermon, G Burda, G Trittenwein, J Golej · Zeitschrift für Geburtshilfe und Neonatologie · 2009 · Heft 04

Dokument
1042776
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Geburtshilfe und Neonatologie
Autor:innen
R Vargha, G Mostafa, M Hermon, G Burda, G Trittenwein, J Golej
Ausgabe
Heft 04 / 2009
Seiten
–
Erschienen: 2009-04-24 00:00:00
ISSN
0948-2393
DOI
10.1055/s-0029-1223045

Zusammenfassung

We report about a term newborn with urea-cycle disorder with severe cerebral edema in which the pharmacological treatment was combined with venovenous hemodiafiltration (VVHDF) and therapeutic hypothermia. A 50h old boy was admitted at a NICU in an external hospital because of convulsions and respiratory failure. Initial metabolic workup showed ammonia 2320µmol/l and the boy was transferred to our hospital. Initial examination showed a ventilated newborn with hepatomegalia and severe hypotension and ammonia concentrations of 2391µmol/l under treatment with Arginin-HCL and Na-Benzoat. Cranial ultrasound (CUS) sho…

Schlagworte

inborn urea-cycle disorder therapeutic hypothermia treatment of cerebral edema venovenous hemodiafiltration Ammonia After Argininosuccinate Lyase Arginin Blood Zeitschrift für Geburtshilfe und Neonatologie