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MR spectroscopy changes and neuropsychometric deficits in patients with renal insufficiency

AB Tryc, G Alwan, M Bokemeyer, A Goldbecker, M Haubitz, K Weissenborn · Aktuelle Neurologie · 2009 · Heft 10

Dokument
1043010
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Aktuelle Neurologie
Autor:innen
AB Tryc, G Alwan, M Bokemeyer, A Goldbecker, M Haubitz, K Weissenborn
Ausgabe
Heft 10 / 2009
Seiten
–
Erschienen: 2009-10-07 00:00:00
ISSN
0302-4350

Zusammenfassung

Introduction: Uremic encephalopathy is normally diagnosed by neurological deficits in patients with chronic renal insufficiency. However, neuropsychological deficits may occur long before any overt neurological symptoms can be observed. Little is known about the underlying brain pathology of patients suffering from uremic encephalopathy. We hypothesized that cognitive deficits present in patients with renal insufficiency treated with and without hemodialysis may correspond to neurometabolite changes in distinct brain regions. Methods: We performed MR-spectrometry in 23 non-dialyzed patients with chronic renal in…

Schlagworte

Attention Executive Function Dialysis Population Creatine Choline Aktuelle Neurologie