CareLit Fachartikel

Prophylactic levetiracetam perioperatively in neurosurgery

KM Schebesch, J Schlaier, A Brawanski, M Lange · Aktuelle Neurologie · 2009 · Heft 10

Dokument
1043031
CareLit-ID
Jahr
2009
Publikation
PDF
nein
Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Aktuelle Neurologie
Autor:innen
KM Schebesch, J Schlaier, A Brawanski, M Lange
Ausgabe
Heft 10 / 2009
Seiten
–
Erschienen: 2009-10-07 00:00:00
ISSN
0302-4350

Zusammenfassung

Objective: To evaluate the prophylactic anticonvulsant use of levetiracetam in craniotomy-patients with contraindications for phenytoin. The prophylactic use of anticonvulsants in Neurosurgery is controversial because the evidence is inconsistent. Phenytoin is the only approved agent for this indication, but it can cause critical drops in blood pressure and heart rate. Therefore the routine prophylactic use of phenytoin for craniotomies needs careful consideration especially in cardiologically compromised patients. Hence, newer antiepileptic drugs (AEDs) with fewer adverse reactions have been recommended for thi…

Schlagworte

Seizures Drug Interactions Anticonvulsants Blood Pressure Anesthesia Population Blood After Aktuelle Neurologie