Distinct fractions of Pelargonium sidoides-extract (EPs® 7630) inhibit adhesion of group A streptococci to epithelial cells
A Janecki, A Conrad, U Frank, H Kolodziej · Zeitschrift für Phytotherapie · 2009 · Heft 08
Bibliografische Angaben
Zusammenfassung
EPs® 7630, a special aqueous-ethanolic extract of the roots of Pelargonium sidoides, showed in vitro antibacterial, antiviral and immunomodulatory properties in several studies [1]. However, the direct antibacterial activities proved to be only weak under therapeutic conditions and speculation about an anti-infective defence mechanism by which EPs® 7630 might exert antibacterial activity was recently guided by consideration of anti-adhesive effects [2]. The demonstrated significant reduction of adhesion of group A streptococci (GAS) to intact epithelial cells prompted the present study to provide a chemical rati…