Influence of the saponins from Hedera helix on the β2-adrenergic responsiveness of living cells investigated by β2-adrenergic receptor internalization studies and determination of…
A Wolf, A Sieben, F Runkel, H Häberlein · Zeitschrift für Phytotherapie · 2009 · Heft 08
Bibliografische Angaben
Zusammenfassung
α-Hederin, hederacoside C and hederagenin are saponins of dry extracts obtained from ivy leaves (Hedera helix L.). These extracts are used in the treatment of obstructive airway diseases characterized by hypersecretion of viscous mucus and coughing. Based on spirometric and plethysmographic measurements, clinical relevant improvements in lung function have been observed, and statistically significant efficacy of a dried ivy leaf extract (5–7,5 : 1) has been shown [1]. Moreover, ivy leaf extracts show spasmolytic activity, reducing smooth muscle spasm in vitro [2], as well as bronchodilatory effects shown in a st…