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Influence of the saponins from Hedera helix on the β2-adrenergic responsiveness of living cells investigated by β2-adrenergic receptor internalization studies and determination of…

A Wolf, A Sieben, F Runkel, H Häberlein · Zeitschrift für Phytotherapie · 2009 · Heft 08

Dokument
1043136
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
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Zeitschrift
Zeitschrift für Phytotherapie
Autor:innen
A Wolf, A Sieben, F Runkel, H Häberlein
Ausgabe
Heft 08 / 2009
Seiten
–
Erschienen: 2009-08-26 00:00:00
ISSN
0722-348X

Zusammenfassung

α-Hederin, hederacoside C and hederagenin are saponins of dry extracts obtained from ivy leaves (Hedera helix L.). These extracts are used in the treatment of obstructive airway diseases characterized by hypersecretion of viscous mucus and coughing. Based on spirometric and plethysmographic measurements, clinical relevant improvements in lung function have been observed, and statistically significant efficacy of a dried ivy leaf extract (5–7,5 : 1) has been shown [1]. Moreover, ivy leaf extracts show spasmolytic activity, reducing smooth muscle spasm in vitro [2], as well as bronchodilatory effects shown in a st…

Schlagworte

After Biochemistry Bronchoconstriction Acetylcholine Calmodulin Arrestin Clathrin Zeitschrift für Phytotherapie