Expression of stem cell factor and its receptor, c-kit, in different rat models of liver injury and regeneration
T Mansuroglu, B Saile, G Ramadori, J Dudas · Zeitschrift für Gastroenterologie · 2007 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims: Stem cell factor (SCF) and its receptor c-kit constitute an important signal transduction system implicated in survival, proliferation and differentiation. However, the changes of the gene expression of the SCF/c-kit gene-system in normal liver, under different conditions of liver injury and regeneration and in different liver cells have not yet been determined. EXPERIMENTAL DESIGN: The expression of SCF and c-kit genes was examined in normal rat liver, in acute phase model of turpentine oil intramuscular injection, in acute and chronic CCl4-induced liver injury, in rat models utilizing partial hepatectomy…