Randomised trial on the use of clarithromycin for prevention of chronic lung disease in preterm infants with isolation of Ureaplasma species within the amniotic cavity at birth

Background: Intrauterine infection with Ureaplasmaspp is associated with an increased risk for the development of chronic lungdisease in preterm infants. The aim of the present study was to determine the effect of postnatal clarithromycin on the development of chronic lung diseasein preterm infants with isolation of Ureaplasma spp. within the amniotic cavityat birth. Patientsand Methods: Amniotic cavity cultures were performed prospectively in preterm deliveries