Mycophenolate mofetil as second line therapy in Autoimmune Hepatitis?
EM Hennes, YH Oo, C Schramm, U Denzer, P Buggisch, C Wiegard, S Kanzler, M Schuchmann, WO Böcher, PR Galle, DH Adams, AW Lohse · Zeitschrift für Gastroenterologie · 2008 · Heft 01
Bibliografische Angaben
Zusammenfassung
Introduction: In patients with autoimmune hepatitis efficient immunosuppressive therapy is essential to avoid progression to cirrhosis. There is no established second line therapy for patients failing standard therapy with steroids and azathioprine. The aim of this study was to examine the possible role of Mycophenolate mofetil (MMF) as second line treatment of autoimmune hepatitis (AIH). Patients and methods: We were able to identify 36 patients (28 women, 8 men) with AIH proven according to International Autoimmune Hepatitis Group-criteria who failed standard therapy. 27 of 36 patients had experienced side eff…
