Deep brain stimulation in the Nucleus accumbens – outcomes after one year stimulation in patients with treatment resistant obsessive compulsive disorder

Background: The effects of deep brain stimulation (DBS) in patients with obsessive compulsive disorder (OCD) have been presented in several case reports, case series and even in two randomized sham controlled long-term observations. Predominantly bilateral stimulation of the anterior limb of the internal capsule was presented. Methods: Results of unilateral stimulation of the right Nucleus accumbens (NAC) after 12 months in 10 patients with severe treatment resistant OCD were reported. Results: Mean Yale-Brown Obsessive Compulsive Scale (Y-BOCS) scores decreased significantly from baseline to one year follow up.…