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Cortical and subcortical structural brain alterations in restless legs syndrome: A whole brain-based MRI approach to in vivo pathoanatomy

A Unrath, HP Müller, F Jüngling, J Kassubek · Klinische Neurophysiologie · 2008 · Heft 04

Dokument
1046236
CareLit-ID
Jahr
2008
Publikation
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DOI
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Bibliografische Angaben

Zeitschrift
Klinische Neurophysiologie
Autor:innen
A Unrath, HP Müller, F Jüngling, J Kassubek
Ausgabe
Heft 04 / 2008
Seiten
–
Erschienen: 2008-04-08 00:00:00
ISSN
1434-0275
DOI
10.1055/s-2008-1072845

Zusammenfassung

Introduction: Various neuroimaging and electro-physiological techniques have demonstrated partly conflicting results of cortical, subcortical, brainstem and spinal alterations in restless legs syndrome (RLS). Thus, up to date, a circumscribed pathoanatomical correlate of this disorder remains still undetermined. By application of the appropriate MRI technique each, i.e. voxel-based morphometry (VBM) for gray matter (GM) and diffusion tensor imaging (DTI) for white matter (WM), the aim of the present study was to address potential alterations in brain anatomy within the same group of patients suffering from idiop…

Schlagworte

Diffusion Tensor Imaging Movement Disorders Association Anisotropy Diffusion Movement Address Anatomy Klinische Neurophysiologie