Functional network properties are altered in focal epilepsies

Introduction: There is currently an increasing interest in developing refined analysis methods that can help to understand the relationship between structure and function in complex systems (1). Recent studies show that new insights into normal and disturbed brain functioning can be achieved by considering the brain as a complex network of interacting dynamical systems (2). A number of analysis methods already allow one to characterize statistical and spectral properties of functionally (e.g. via EEG or MEG recordings) defined networks, and the mean path length L and the cluster coefficient C have been widely us…