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Deep brain stimulation of the thalamus as a treatment of intractable Tourette Syndrome

C Plewnia, L Rzesnitzek, F Schober, S Soekadar, T Wächter, A Gharabaghi, R Krüger · Klinische Neurophysiologie · 2008 · Heft 04

Dokument
1046248
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Jahr
2008
Publikation
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Bibliografische Angaben

Zeitschrift
Klinische Neurophysiologie
Autor:innen
C Plewnia, L Rzesnitzek, F Schober, S Soekadar, T Wächter, A Gharabaghi, R Krüger
Ausgabe
Heft 04 / 2008
Seiten
–
Erschienen: 2008-04-08 00:00:00
ISSN
1434-0275
DOI
10.1055/s-2008-1072965

Zusammenfassung

Gilles de la Tourette Syndrome (TS) is a chronic neuropsychiatric disorder characterised by multiple motor tics and one or more phonic (vocal) tics. 90% of patients have comorbid disorders including attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), self-injurious behaviours, depression and anxiety. Treatment of TS includes typical and atypical neuroleptics, alpha-adrenergic agonists, benzo-diazepines and behavioural interventions. Recently, a number of case reports and case series have demonstrated that deep brain stimulation (DBS) targeting the centromedian-parafascicular com…

Schlagworte

After Depression Adrenergic Agonists Bipolar Disorder Internal Capsule Observation Attention Anxiety Klinische Neurophysiologie