Diffusion Tensor Imaging (DTI) in idiopathic REM sleep behaviour disorder (iRBD)
M Belke, MM Unger, K Hattemer, JT Heverhagen, B Keil, K Stiasny-Kolster, F Rosenow, NJ Diederich, G Mayer, JC Möller, WH Oertel, S Knake · Klinische Neurophysiologie · 2010 · Heft 03
Bibliografische Angaben
Zusammenfassung
Introduction: Idiopathic REM sleep behaviour disorder (iRBD) – a parasomnia characterized by dream enactments – is a risk factor for the development of Parkinson's disease (PD) and other alpha-synucleinopathies. The pathophysiology of iRBD is likely due to dysfunction of brainstem nuclei that regulate REM sleep. Material and Methods: Diffusion Tensor Imaging (DTI) of the brain is a method for studying the microstructural brain tissue integrity in vivo. We investigated whether DTI detects microstructural abnormalities in brains of patients with iRBD – compared with age-matched controls – as a potential in vivo in…
