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Paraneoplastic Lambert-Eaton Myasthenic Syndrome with unusual neurophysiological findings

P Kern, M Entscheva, J Faiss · Klinische Neurophysiologie · 2010 · Heft 03

Dokument
1046660
CareLit-ID
Jahr
2010
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Neurophysiologie
Autor:innen
P Kern, M Entscheva, J Faiss
Ausgabe
Heft 03 / 2010
Seiten
–
Erschienen: 2010-03-02 00:00:00
ISSN
1434-0275
DOI
10.1055/s-0030-1251005

Zusammenfassung

Introduction: The Lambert-Eaton myasthenic syndrome (LEMS) is an uncommon presynaptic neuromuscular junction disorder, occurring as an autoimmune and also paraneoplastic disease. The characteristic neurophysiological abnormalities are a reduced compound motor action potential (CMAP), usually less then 2 mV, as well as a massive increment after tonic preinnervation or serial high frequency stimulation >20 hz. Case report: We saw a 69 years old woman, who complained of progredient gait disturbance since several weeks, which became worse during the day. She had a history of diabetes mellitus and smoking (45 pj), no…

Schlagworte

After Diabetes Mellitus Bronchoscopy Antibodies Diagnosis Calcium Klinische Neurophysiologie