Medium chain acylcarnitines are exercise-related biomarkers with the potency to enhance fatty acid oxidation
C Weigert, X Zhao, P Simon, E Fehrenbach, M Hoene, J Wang, ED Schleicher, HU Häring, G Xu, AM Niess, R Lehmann · Diabetologie und Stoffwechsel · 2010 · Heft 04
Bibliografische Angaben
Zusammenfassung
Aims: Metabolomics is a powerful tool to investigate complex metabolic processes. The term stands for the non-targeted, comprehensive analysis of metabolites. Here it is used to identify exercise-related biomarkers as potential signaling molecules that are involved in the beneficial adaptation to regular physical activity. Methods: In the presented non-targeted metabolomics approach, applying liquid chromatography-qTOF-mass spectrometry, the plasma metabolome of thirteen endurance-trained men before, directly after a 60min continuous run at 93% VIAT on a treadmill, and after 3h and 24h of recovery phase was inve…