Interplay of lung cells and their cellular responses upon exposure to combustion-generated ultrafine particles and manufactured nanoparticles
B Rothen-Rutishauser, F Blank, L Müller, C Mühlfeld, P Gehr · Pneumologie · 2008 · Heft 04
Bibliografische Angaben
Zusammenfassung
Besides a series of structural and functional barriers, which protect the respiratory system from inhaled particulate antigen, respiratory diseases are frequent and increasing. Many epidemiologic studies have shown a direct relationship between ambient air pollution and increased health effects. Moreover, recent studies indicate that manufactured nanoparticles are at least as toxic. Manufactured nanomaterials with new chemical and physical properties are produced constantly and the toxicity of these particles is unknown. The potential human health benefits of nanotechnology are undoubted, however, occupational e…