Second trimester quadruple test as a predictor of adverse obstetric outcome

Objective: To investigate the efficacy of quadruple test during the second trimester as a predictor of adverse obstetric outcome. Methods: By retrospective review, we evaluated data of maternal and newborn records of women who had quadruple test during 15–18weeks to identify associations between the quadruple test and preeclampsia, preterm birth, intrauterine growth restriction, hyperemesis gravidarum and gestational diabetes. Results: we analyzed data from 355 pregnancies. The risk of low birth weight(£2.4kg) increased significantly if a patient had α-fetoprotein(AFP)³ 2.0MoM (odds ratio[OR] 10.0, CI 2.9–35.1),…