Antenatal steroids administered to induce fetal lung maturation affect higher cortical functions–a fetal magnetoencephalography (fMEG) study
U Schneider, C Arnscheidt, M Schwab, J Haueisen, HJ Seewald, E Schleussner · Ultraschall in der Medizin - European Journal of Ultrasound · 2008 · Heft 05
Bibliografische Angaben
Zusammenfassung
Objective: Steroid administration prior to 34 gestational weeks to accelerate fetal lung maturation reduces neonatal morbidity and mortality in case of preterm delivery. Concerns of cerebral side effects emerged from experimental studies. Our aim was to investigate the effect of therapeutic betamethasone administration on human fetal cortical stimulus processing utilizing auditory evoked responses (CAER) recorded by fetal magnetoencephalography (fMEG). Methods: An intra–individual comparison of the CAER latency prior to and within six hours after treatment with 2×12mg betamethasone i.v. 24h apart for preterm lab…