Regeneration profiling of human gastric glands: differences between fundic and antral surface mucous cells

Introduction: Maintenance of the surface integrity of mucous epithelia is vital for physiological functions of many organs such as the stomach. The human gastric mucosa can be divided into three different functional regions, i.e., the cardia, the corpus, and the antrum. Classically, the cellular constituents are defined as surface mucous cells (SMCs)/gastric pit cells, oxyntic cells, mucous neck and antral gland cells, zymogenic cells and endocrine cells. Here, a first expression profile of human gastric glands is presented using RT-PCR analysis after laser microdissection. Material and Methods: Double immunfluo…