CareLit Fachartikel

Association of JAK-STAT pathway related genes with lymphoma risk

K Butterbach, S Behrens, S de Sanjosé, Y Benavente, N Becker, L Foretova, M Maynadie, P Cocco, A Staines, P Boffetta, P Brennan, A Nieters · Das Gesundheitswesen · 2010 · Heft 09

Dokument
1047828
CareLit-ID
Jahr
2010
Publikation
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Das Gesundheitswesen
Autor:innen
K Butterbach, S Behrens, S de Sanjosé, Y Benavente, N Becker, L Foretova, M Maynadie, P Cocco, A Staines, P Boffetta, P Brennan, A Nieters
Ausgabe
Heft 09 / 2010
Seiten
–
Erschienen: 2010-09-02 00:00:00
ISSN
0941-3790
DOI
10.1055/s-0030-1266455

Zusammenfassung

Background: Non-Hodgkin Lymphoma (NHL) belong to the seventh most common cancer in Europe and constitute the tenth most commonly diagnosed cancer worldwide. Apart from risk factors such as certain infectious agents and immunodeficiency syndromes, genetic variants related to immunity have been associated with lymphomagenesis. Previous studies suggested an important role of the JAK-STAT signalling pathway in tumour development. Therefore, we explored genetic variants in the JAK-STAT pathway associated with lymphoma risk. Material and Methods: In total, 1481 lymphoma cases and 1491 age, sex and study centre matched…

Schlagworte

Das Gesundheitswesen