Motor deficit of hand and arm movements in manifest hepatic encephalopathy before and after therapy with L-ornithin-L-aspartat

Background and Aims: Impaired hand function is a frequent finding in movement disorders. Grip force analysis is a highly sensitive method to document even subtle impairments of finger force control and may be used both as a diagnostic tool and for the objective evaluation of treatment in neurological movement disorders. Hepatic encephalopathy (HE) is characterized by a large variety of symptoms including postural tremor or motor deficit of hand and arm movements. It is unclear if an improvement can be obtained by medical therapy. The present study was designed to quantitatively assess the influence of HE on gras…