Unusual manifestation of B-cell acute lymphoblastic leukemia in a 16-year-old boy with gastric ulcer caused by blast infiltration

We present the case of a 16-year-old boy diagnosed with B-cell acute lymphoblastic leukemia and leukemic infiltration of the stomach. Two months prior to diagnosis, the patient had suffered from upper abdominal pain with vomiting, melena, increasing tiredness accompanied by weight loss of 12kg and night sweat. He presented to a local hospital where a stenosing pyloric ulcer was diagnosed by gastroscopy. Biopsy specimen were taken and consistent with chronic inflammatory changes. Colonization with Helicobacter pylori was found and eradication therapy was initiated. However, two months later the patient presented…