Confirmation of high SVR rates after shortening duration of treatment with Peginterferon alfa–2a (PEG) and Ribavirin (RBV) in Chronic Hepatitis C (CHC) Patients with RVR in Real L…
D Hüppe, S Mauss, T Lutz, M Schuchmann, G Moog, A Schober, R Heyne, C John, W Schiffelholz, C Eisenbach, G Teuber, A Baumgarten, E Schott, U Alshuth, P Buggisch · Zeitschrift für Gastroenterologie · 2012 · Heft 01
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Zusammenfassung
Studies showed that SVR in patients with low viral load (LVL) is high and treatment duration can be reduced while maintaining high SVR rates. But is this true under real life conditions? Methods: Between 2008 and 2011 data of 3810 patients completing a treatment period of 6 months for GT 2/3 or 12 months for GT 1 plus 6 months follow-up were recorded in a noninterventional study. This analysis included 745 naïve patients of G–1/2/3 with RVR and achievement of planned end of therapy, 165 patients of them got shortened treatment: GT 1 20–28 wks (n=110) and GT 2/3 (n=55) 14–18 wks in comparison to standard duration…