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Reverse Phase Protein Array (RPPA) of High Risk ALL

F Seyfried, B Accordi, M Queudeville, SM Eckhoff, G Milani, L Galla, M Giordan, J Kraus, G Basso, H Kestler, G te Kronnie, KM Debatin, LH Meyer · Klinische Pädiatrie · 2012 · Heft 04

Dokument
1049458
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Jahr
2012
Publikation
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Pädiatrie
Autor:innen
F Seyfried, B Accordi, M Queudeville, SM Eckhoff, G Milani, L Galla, M Giordan, J Kraus, G Basso, H Kestler, G te Kronnie, KM Debatin, LH Meyer
Ausgabe
Heft 04 / 2012
Seiten
–
Erschienen: 2012-04-27 00:00:00
ISSN
0300-8630
DOI
10.1055/s-0032-1310475

Zusammenfassung

In a NOD/SCID/huALL model we have recently shown that short time to leukemia (TTLshort) of xenografted patient samples determines poor patient outcome. In this study we analyzed 16 xenografted BCP-ALL samples using RPPA and validated the findings by Western Blot. Comparison of the protein expression data in short vs. long TTL subgroups (shrinkage t-test, P

Schlagworte

Klinische Pädiatrie