Immune response to influenza vaccine and frequency of influenza virus infection in patients with inflammatory bowel disease on maintenance immunosuppressive therapy – Pilot study

Introduction: Inflammatory bowel disease (IBD) patients on immunosuppressive therapy are at increased risk of infective diseases. Influenza vaccination is recommended for patients with IBD. This study aimed to evaluate the serologic and clinical immune response to influenza vaccine in immuncompromised IBD patients. Patients and methods: In this prospective study, influenza vaccination was recommended for 29 IBD patients treated with immunosuppressive or biological therapy. 14 IBD patients (5 Crohn's disease, 9 ulcerative colitis, mean age at the diagnosis: 27 years) were vaccinated. We collected serum samples fo…