Secondary Sclerosing Cholangitis in Critically Ill Patients: MELD score and renal function predict outcome
T Voigtländer, AA Negm, A Schneider, CP Strassburg, MP Manns, J Wedemeyer, TO Lankisch · Zeitschrift für Gastroenterologie · 2013 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background and Aims: Secondary sclerosing cholangitis in critical ill patients (SSC-CIP) is an under-diagnosed emerging disease entity. SSC-CIP is characterized by progressive bile duct destruction leading to end-stage liver disease and eventual liver failure. The exact pathological mechanisms and clinical risk factors have not been conclusively elucidated. Our aim was to characterize key features of the clinical presentation of SSC-CIP and to identify prognostic factors for mortality. In addition, we evaluated the accuracy of abdominal ultrasound and the clinical relevance of routine bile collection. Methods: 5…
