Progressive Allograft Dysfunction Following Lung Transplantation: First Experience with Pirfenidone – A Case Report

Background: Chronic lung allograft dysfunction (CLAD) is one of the major factors limiting graft function after lung transplantation (LuTx). No effective medical treatment is available but animal experiments with pirfenidone have shown some promise. The aim of this case report was to evaluate pirfenidone in a LuTx recipient with progressive CLAD. Methods: Descriptive data analysis was performed prospectively based on lung function testing, functional outcome and quality of life valuation. Results: Our case is a 56-year-old female LuTx recipient who underwent LuTx in 2009 due to idiopathic pulmonary fibrosis acco…