A multi-centre proof of concept study to assess efficacy and safety of endoscopic hemostasis with combined activated Factors IIa, VIIa, IXa and Xa (Seraseal/Fastact ®) in patients…
A Ferlitsch, P Salzl, A Püspök, F Wewalka, R Schöfl, H Lenzen, T Lankisch, E Brownstone, C Madl, W Dolak, M Ferlitsch · Zeitschrift für Gastroenterologie · 2013 · Heft 05
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Zusammenfassung
Introduction: Endoscopic treatment of severe gastrointestinal bleeding can be difficult and high technical expertise is required. A simple and effective method of endoscopic hemostasis would have a significant impact on treatment success. Aim of the study is to assess the efficacy and safety of endoscopic hemostasis with combined activated factors IIa/VIIa/IXa/Xa (Seraseal, Wortham Laboratories, USA). Methods: Patients with active gastrointestinal bleeding were included. 5 ml Seraseal was topically applied via a standard delivery catheter to the bleeding site. In group A, Seraseal was applied as intital method f…