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Xanthohumol inhibits the development of non-alcoholic steatohepatitis by systemic as well as direct effects on hepatocellular lipid uptake

C Dorn, A Mahli, WE Thasler, M Müller, C Hellerbrand · Zeitschrift für Gastroenterologie · 2013 · Heft 08

Dokument
1051281
CareLit-ID
Jahr
2013
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
C Dorn, A Mahli, WE Thasler, M Müller, C Hellerbrand
Ausgabe
Heft 08 / 2013
Seiten
–
Erschienen: 2013-08-16 00:00:00
ISSN
0044-2771

Zusammenfassung

There is growing interest in phenolic compounds and their presumed role in the prevention of various degenerative diseases. Xanthohumol, the principal prenylated flavonoid of the female inflorescences of the hop plant, has been most extensively studied as cancer chemopreventive agent. In addition, anti-inflammatory properties have been demonstrated in various organs including the liver. Nonalcoholic fatty liver disease (NAFLD) is considered as hepatic manifestation of the metabolic syndrome, and in a subset of cases hepatic steatosis progresses to steatohepatitis (NASH), which may further advance with significan…

Schlagworte

Blood Glucose Obesity Blood Diet Lead Zeitschrift für Gastroenterologie