Incidence and predictors of aspiration pneumonia in endoscopic sedation

Study aims: We investigated the incidence of aspiration pneumonie during outpatient endoscopic sedation. Methods: 24.441 patients received endoscopic sedation with either Propofol mono or Propofol in combination with Midazolam during EGD or colonoscopy. We prospectively assessed signs for aspiration pneumonia in a questionnaire that 15.690 patients completed 24 hours after the endoscopic procedure. Using multivariate analysis we screened for predictors of aspiration pneumonia during endoscopic sedation. Results: 829 of the 15.690 patients reported newly developed coughing the day after the examination (5.3%). In…