Effect of dexamethasone on circulating leptin levels during pregnancy
GO Ajayi · Zeitschrift für Geburtshilfe und Neonatologie · 2013 · Heft 11
Bibliografische Angaben
Zusammenfassung
Background: Leptin, the protein product of the Ob gene, is thought to have a role in signaling safety through hypothalamic pathways. Glucocortisteroids are potent stimulation of both Ob gene expression and circulating Leptin in animals and powerful appetite stimulants in humans. Usage in pregnant women has limits, more for fetal lung maturation. Setting: A Tertiary Prenatal Diagnosis and Therapy Centre and Dept. of Obstetrics & Gynecology of the University of Lagos, Lagos, Nigeria. Aim: We investigated circulating Leptin response to administration of dexamethasoneduring pregnancy. Methods and Material: In n = 13…