Differential behavioural and physiological effects of anodal transcranial direct current stimulation in healthy adults of younger and older age

Purpose: γ-amino-butric acid (GABA)-mediated inhibition has been proposed to constitute a potential target of anodal transcranial direct current stimulation (atDCS). This could be an interesting option to potentially target conditions marked by deficient inhibitory activity as shown for healthy aging. Therefore, the aim of the present work was to analyse the effect of atDCS on resting-state and event-related inhibition and its association with stimulation-induced change in motor behaviour. Methods: After-effects of a single session of atDCS on resting-state and event-related short-interval intracortical inhibiti…