Neural oscillatory evidence of compensatory inhibitory mechanisms in Tourette patients
V Niccolai, S Franzkowiak, J Finis, M Südmeyer, M Jonas, G Thomalla, HR Siebner, K Müller-Vahl, A Münchau, A Schnitzler, K Biermann-Ruben · Klinische Neurophysiologie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Introduction: It has been proposed that individuals with Gilles de la Tourette syndrome (TS) gain control over their tics through the development of compensatory inhibitory self-regulation mechanisms. Aims: We tested the presence of inhibitory patterns in the beta (15 – 25 Hz) frequency range, a rhythm that is typically related to motor functions. Specifically, we predicted an enhanced beta rebound in Tourette subjects as a signature of increased inhibitory mechanisms. Methods: Magnetoelectroencephalographic (MEG) signals were measured from 12 TS patients with no comorbidities and 12 control subjects matched for…
