Treatment of chronic Hepatitis C Genotype 1 (G1) infection with Boceprevir (BOC) in German Real-Life: Impact of Hemoglobin (Hb) decline on virologic response
G Teuber, P Buggisch, H Löhr, H Steffens, M Kraus, C John, P Geyer, B Weber, T Witthoeft, A Herrmann, M Hoesl, U Naumann, T Dahhan, D Hartmann, B Dreher, M Bilzer · Zeitschrift für Gastroenterologie · 2014 · Heft 08
Bibliografische Angaben
Zusammenfassung
Background: Data regarding the severity and impact of hemoglobin (Hb) decline caused by triple therapy with boceprevir (BOC) in real-life are still scarce and were evaluated in the present interim analysis of the German NOVUS observational study. Methods: From April 2012 until November 2013, 469 patients with G1 infection were recruited in the ongoing NOVUS study by 97 practices and hospitals in Germany. Patients were treated with pegylated interferons (PegIFN) and ribavirin (RBV) together with BOC for 24 to 44 weeks after a 4 week lead-in period with PegIFN/RBV. The present interim analysis was restricted to 15…