German EndoBarrier® Registry – conception, structure, and current status

Background: Obesity and type 2 diabetes mellitus are widespread and cost-intensive-diseases. Current conservative-therapeutic-concepts regularly fail to reach therapeutic-targets. Even though bariatric-surgery has proven to be effective, it is not suitable for all patients. A less-invasive approach is the temporary, endoscopic duodenal-jejunal bypass-sleeve (DJBS, EndoBarrier®). It consists of a self-expanding-mesh and an impermeable-shell of 60 cm mimicking a Roux-en-Y gastric bypass with exclusion of the proximal-small-intestine. Up to now, small prospective-studies have demonstrated promising improvements of…