Are extraintestinal manifestations associated with disease outcomes in inflammatory bowel diseases? Results from the Veszprem population based inception cohort database

Background and Aims: Association between extraintestinal manifestations (EIM) and disease activity suggest a common pathogenic link. Limited data are available on the effect of EIMs on the long-term disease course in inflammatory bowel diseases (IBD). The aim of this study was to analyze the association between the presence of EIMs (joint, skin, eyes) and treatment steps and long term disease outcomes in the population-based inception cohort in the Veszprem province database after 1977. Methods: A well-characterized Hungarian cohort of 506 incident cases with Crohn's disease (male/female: 251/255, age at diagnos…