High-intensity interval training improves peripheral insulin sensitivity and mitochondrial respiration in patients with type 2 diabetes
M Apostolopoulou, M Röhling, S Gancheva, T Jelenik, K Kaul, A Bierwagen, JOJ Lundbom, K Müssig, J Szendroedi, M Roden · Diabetologie und Stoffwechsel · 2016 · Heft 04
Bibliografische Angaben
Zusammenfassung
High intensity interval training (HIT) is a time-efficient training concept mostly studied in healthy populations. We hypothesized that HIT improves hepatic and peripheral insulin sensitivity and increases muscle mitochondrial function in patients with type 2 diabetes. To this end, we examined 11 sedentary male patients with type 2 diabetes (age: 58 ± 6 years, BMI: 31.1 ± 2.5 kg.m-2), who performed a 12-week cycling protocol (4 × 4 min intervals at 85% of maximal heart rate, three minutes recovery, three days weekly) at baseline, after one bout, after 12 weeks of HIT and after 4 weeks of detraining. Two-step hyp…
