Adalimumab therapy may exhibit a positive influence on anxiety in patients suffering from Crohn's Disease

Introduction: Crohn's disease (CD) is frequently accompanied by mental disorders including anxiety or depression. This study explores if adalimumab (ADA) is not only effective for CD but shows positive effects on anxiety as well. Method: In this non-interventional study, ADA was prescribed to 83 adult CD patients according to clinical practice at Austrian hospitals. At three visits (V0 at baseline, V1 after 12 and V2 after 24 weeks), clinical activity was assessed using the Harvey-Bradshaw Index (HBI), anxiety was estimated by the State-Trait Anxiety Inventory for Adults (STAI) and the Hospital Anxiety and Depre…